A team from University of Toronto Engineering is the first to synthesize long noncoding RNA (lncRNA) outside the cell—a new approach to drug discovery that has already yielded some promising ...

Colorectal cancer (CRC) remains one of the most prevalent and deadly cancers worldwide, with rising incidence linked to dietary and lifestyle changes. Despite advances in surgery and chemotherapy, ...

Explore the breakthrough of lab-made lncRNA by University of Toronto Engineering for new drug discovery potential.

When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...

Scientists at the University of Pittsburgh, together with colleagues at the University of Pittsburgh School of Medicine and University of Pittsburgh Cancer Institute, have identified how a long ...

Several types of RNA help regulate gene expression, and a number of these transcripts have been linked to Alzheimer’s disease. However, no one has comprehensively examined how the regulatory RNA ...

circRNA, circular RNA; dsRNA, double-stranded RNA; lncRNA, long non-coding RNA; mRNA, messenger RNA; miRNA, microRNA; ncRNA, non-coding RNA; pre-miRNA, precursor ...

There are plenty of unanswered questions about the origin of life on Earth. But the research community has largely reached consensus that one of the key steps was the emergence of an RNA molecule that ...

On Tuesday, Nobel laureate Thomas Cech spoke at the I Hotel and Conference Center in Champaign about his groundbreaking research on ribonucleic acid, also known as RNA. Cech’s talk covered the ...