A team of researchers has constructed the most detailed single-cell map of the adult human prostate to date, cataloging more ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

A new single-cell atlas shows how epigenetic changes reshape brain cells during aging, revealing genomic instability, ...

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

Andreas Pfenning discusses the techniques being developed and used to study neuronal heterogeneity and the therapeutic potential of his work.

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...

This Research Topic is the second volume of the “Unraveling Breast Cancer Complexity: Insights from Single-Cell Sequencing and Spatial Transcriptomics” ...

Mount Sinai researchers have published the first organ-wide human skin spatial atlas from across the body. It provides an ...

Prostate cancer affects one in five Australian men, making it the most common cancer in the country. Now, researchers at the ...