The disposition of immunoglobulins (IgGs) is influenced by target-dependent and target-independent mechanisms. Target-independent clearance (CLind) of monoclonal antibodies (mAbs) is primarily ...

From protein translation to mitosis, fundamental cellular processes are multifaceted and dynamic. Researchers seeking to understand the inner workings of a cell benefit from multidisciplinary ...

Proteins, one of the smallest building blocks of life on Earth, hold promise for answering some of biology's biggest ...

A team of researchers has developed a method that could transform the field of protein engineering. The new approach, called AI-informed Constraints for protein Engineering (AiCE), enables rapid and ...

Enzymes in laundry detergents, insulin for diabetes, and the antibodies and enzymes used in medicine: all of these exist thanks to protein science and engineering. Protein engineering has transformed ...

Proteins Mosaic Q is a global citizen-science initiative that invites volunteers to help confirm a newly identified structural pattern in the three-dimensional architecture of proteins. The project ...

Plant cell-based bioproduction systems are known for producing proteins with proper folding and post-translational modifications that have been used in a handful of approved therapeutics. Widespread ...

Cradle, the platform that helps scientists to design and program proteins, today published the findings of its first BioDeveloper survey, exploring the methods and priorities of biodevelopers to build ...

Structural biology is shifting from predicting protein shapes to uncovering broader organizational rules; AI tools like AlphaFold have made large-scale protein structure data far ...

Antibody engineering enables the generation of novel and diverse antibody constructs. The development of therapeutic antibodies is highly dependent on antibody engineering, whether for the generation ...