In a French criminal trial, conventional DNA analysis couldn’t distinguish between twin brothers, but emerging scientific methods could help in such cases.

Phylogenetic analysis and DNA sequence representation are foundational pillars in modern molecular biology and bioinformatics. These approaches not only facilitate the reconstruction of evolutionary ...

Roche has put forward a new approach to genetic analysis, which it describes as sequencing-by-expansion—a proprietary method that pulls apart the DNA molecule and amplifies the signal of each ...

Knowing how human DNA changes over generations is essential to estimating genetic disease risks and understanding how we evolved. But some of the most changeable regions of our DNA have been ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

DNA methylation is a highly studied epigenetic modification that is involved in regulating genome function and plays fundamental roles in development and disease. 1 It is linked to a broad range of ...

The genome is more than a linear code; it is a dynamic structure whose three-dimensional folding dictates how genes are regulated. Traditional sequencing technologies capture base-level variation but ...

Students take samples of water and the microscopic creatures within at the Alviso Marina County Park. (Image by Erika Cardema) At the Alviso Marina County Park, reddish-brown water laps at the edge of ...

MASSIVELY parallel sequencing (MPS) has transformed forensic DNA analysis by allowing scientists to examine multiple DNA markers simultaneously and in far greater detail than earlier methods. Despite ...

If you liked this story, share it with other people. Tyler Kartzinel likens protecting biodiversity to enhancing cellphone networks. His analogy is pretty straightforward: look for gaps in coverage, ...

Transcriptomic Predictors of Survival for Palbociclib + Endocrine Therapy Versus Capecitabine in Aromatase Inhibitor–Resistant Breast Cancer From the GEICAM/2013-02 PEARL Trial Our findings revealed a ...

Market Outlook and Growth TrajectoryThe global next generation sequencing market is poised to experience robust expansion, registering an estimated growth rate of around 15% over the next five years.