Approximately 400,000 cases of infantile and childhood hydrocephalus occur worldwide annually. 1 For most affected patients, treatment is inadequate because of limited access to care. Left untreated, ...
The space between the arachnoid and pia meningeal layers encasing the brain is a landscape of connective tissue, blood vessels, and cerebrospinal fluid. Scientists debate how that fluid moves within ...
The typical signs and symptoms of idiopathic NPH are shown. In a retrospective study involving 418 patients with shunt-responsive idiopathic NPH, 96% of the patients had gait difficulty, 76% had ...
Chiari malformation type I (CMI) is a congenital neurological disorder characterized by the herniation of cerebellar tonsils through the foramen magnum, leading to impaired cerebrospinal fluid (CSF) ...
A novel blood and cerebrospinal fluid (CSF) measure showed promise as a biomarker for Parkinsonian disorders. CSF levels of DOPA decarboxylase (DDC) -- an enzyme that converts levodopa into dopamine - ...
New research shows that a cocktail of drugs already approved to treat high blood pressure quickly reduces brain swelling and improves outcomes in animal models of brain injury. Cerebral edema, the ...
Impact of Broadening Trial Eligibility Criteria on the Inclusion of Patients With Brain Metastases in Cancer Clinical Trials: Time Series Analyses for 2012-2022 Effective diagnosis, prognostication, ...
With age, the brain’s ability to clear aggregating proteins such as Aβ wanes. In the November 9 Nature, researchers led by Jonathan Kipnis at Washington University in St. Louis suggest a reason why.
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